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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 21-30 of 65 results.
Fimepinostat in Treating Brain Tumors in Children and Young Adults
Status: Recruiting
Last Changed: Sep 03, 2020
First Received: Mar 28, 2019
Disease(s): Diffuse Intrinsic Pontine Glioma, Recurrent Anaplastic Astrocytoma, Recurrent Glioblastoma, Recurrent Malignant Glioma, Recurrent Medulloblastoma
Intervention(s): Fimepinostat, Therapeutic Conventional Surgery
Locations: Rady Children's Hospital, San Diego, California, United States
University of California, San Francisco, San Francisco, California, United States
University of Florida, Gainesville, Florida, United States
Johns Hopkins Hospital, Baltimore, Maryland, United States
Dana Farber Cancer Institute, Boston, Massachusetts, United States
... and 3 other locations.
Volitinib in Treating Participants With Recurrent or Refractory Primary CNS Tumors
Status: Recruiting
Last Changed: Sep 23, 2020
First Received: Jul 26, 2018
Disease(s): Primary Central Nervous System Neoplasm, Recurrent Diffuse Intrinsic Pontine Glioma, Recurrent Malignant Glioma, Recurrent Medulloblastoma, Refractory Diffuse Intrinsic Pontine Glioma, Refractory Malignant Glioma, Refractory Medulloblastoma
Intervention(s): Savolitinib
Locations: Children's Hospital Los Angeles, Los Angeles, California, United States
Lucile Packard Children's Hospital Stanford University, Palo Alto, California, United States
Children's Hospital Colorado, Aurora, Colorado, United States
Lurie Children's Hospital-Chicago, Chicago, Illinois, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
... and 5 other locations.
SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors
Status: Recruiting
Last Changed: Feb 18, 2020
First Received: Feb 15, 2018
Disease(s): Anaplastic Astrocytoma, Anaplastic Ependymoma, Anaplastic Ganglioglioma, Anaplastic Meningioma, Anaplastic Oligodendroglioma, Pleomorphic Xanthoastrocytoma, Anaplastic, Atypical Teratoid/Rhabdoid Tumor, Brain Cancer, Brain Tumor, Central Nervous System Neoplasms, Choroid Plexus Carcinoma, CNS Embryonal Tumor With Rhabdoid Features, Ganglioneuroblastoma of Central Nervous System, CNS Tumor, Embryonal Tumor of CNS, Ependymoma, Glioblastoma, Glioma, Glioma, Malignant, Medulloblastoma, Medulloblastoma; Unspecified Site, Medulloepithelioma, Neuroepithelial Tumor, Neoplasms, Neoplasms, Neuroepithelial, Papillary Tumor of the Pineal Region (High-grade Only), Pediatric Brain Tumor, Pineal Parenchymal Tumor of Intermediate Differentiation (High-grade Only), Pineoblastoma, Primitive Neuroectodermal Tumor, Recurrent Medulloblastoma, Refractory Brain Tumor, Neuroblastoma. CNS, Glioblastoma, IDH-mutant, Glioblastoma, IDH-wildtype, Medulloblastoma, Group 3, Medulloblastoma, Group 4, Glioma, High Grade, Neuroepithelial Tumor, High Grade, Medulloblastoma, SHH-activated and TP53 Mutant, Medulloblastoma, SHH-activated and TP53 Wildtype, Medulloblastoma, Chromosome 9q Loss, Medulloblastoma, Non-WNT Non-SHH, NOS, Medulloblastoma, Non-WNT/Non-SHH, Medulloblastoma, PTCH1 Mutation, Medulloblastoma, WNT-activated, Ependymoma, Recurrent, Glioma, Recurrent High Grade, Glioma, Recurrent Malignant, Embryonal Tumor, NOS, Glioma, Diffuse Midline, H3K27M-mutant, Embryonal Tumor With Multilayered Rosettes (ETMR), Ependymoma, NOS, WHO Grade III, Ependymoma, NOS, WHO Grade II, Medulloblastoma, G3/G4, Ependymoma, RELA Fusion Positive
Intervention(s): Gemcitabine, ribociclib, sonidegib, trametinib, filgrastim
Locations: St. Jude Children's Research Hospital, Memphis, Tennessee, United States
Child's Study of the Impact of PF Lesion on Motor Skills, Language, Cognitive Functioning and Social Cognition
Status: Not yet recruiting
Last Changed: Nov 22, 2019
First Received: Nov 22, 2019
Disease(s): Medulloblastoma, Childhood, Healthy Volunteers, Fossa Posterior Tumor, Low-grade Glioma
Intervention(s): Functional Magnetic Resonance Imaging (fMRI)
Locations: Hôpital Necker, Paris, France
Institut Curie, Paris, France
Hôpitaux Saint-Maurice, Saint-Maurice, France
Gustave Roussy, Villejuif, France
NKG2D-based CAR T-cells Immunotherapy for Patient With r/r NKG2DL+ Solid Tumors
Status: Not yet recruiting
Last Changed: Sep 15, 2020
First Received: Feb 17, 2020
Disease(s): Hepatocellular Carcinoma, Glioblastoma, Medulloblastoma, Colon Cancer
Intervention(s): NKG2D-based CAR T-cells
Locations: Affiliated hospital of jiujiang university, Jiujiang, Jiangxi, China
Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG
Status: Recruiting
Last Changed: Jul 24, 2020
First Received: Aug 08, 2019
Disease(s): Glioblastoma, Medulloblastoma, Ependymoma, Diffuse Intrinsic Pontine Glioma
Intervention(s): Indoximod, Partial Radiation, Full-dose Radiation, Indoximod, Temozolomide, Cyclophosphamide, Etoposide, Lomustine
Locations: Augusta University, Georgia Cancer Center, Augusta, Georgia, United States
Emory University, Children's Heathcare of Atlanta, Druid Hills, Georgia, United States
Study of Stored Tumor Samples in Young Patients With Brain Tumors
Status: Recruiting
Last Changed: Jul 31, 2020
First Received: May 12, 2009
Disease(s): Brain and Central Nervous System Tumors
Locations: St. Jude Children's Research Hospital, Memphis, Tennessee, United States
Dosimetry-Guided, Peptide Receptor Radiotherapy (PRRT) With 90Y-DOTA- tyr3-Octreotide (90Y-DOTATOC)
Status: Recruiting
Last Changed: Jun 21, 2019
First Received: Sep 06, 2017
Disease(s): Neuroendocrine Tumors, Meningioma, Neuroblastoma, Medulloblastoma
Intervention(s): 90Y-DOTA tyr3-Octreotide, 68Ga-DOTATOC PET Positron Emission Tomography (PET) whole body scan, Amino Acids
Locations: University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States
Rare CNS Tumors Outcomes &Risk
Status: Recruiting
Last Changed: May 27, 2020
First Received: Aug 16, 2017
Disease(s): High Grade Meningioma, Ependymoma, Medulloblastoma, PNET, Primary CNS Sarcoma
Locations: National Cancer Institute (NCI), Bethesda, Maryland, United States
Immune Checkpoint Inhibitor Nivolumab in People With Select Rare CNS Cancers
Status: Recruiting
Last Changed: Apr 20, 2020
First Received: Jun 02, 2017
Disease(s): Medulloblastoma, Ependymoma, Pineal RegionTumors, Choroid Plexus Tumors, Atypical/Malignant Meningioma
Intervention(s): Nivolumab
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland, United States