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Malignant peripheral nerve sheath tumor

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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 1-10 of 15 results.
A Study of Pembrolizumab in Patients With Malignant Peripheral Nerve Sheath Tumor (MPNST), Not Eligible for Curative Surgery
Status: Recruiting
Last Changed: Mar 05, 2020
First Received: Feb 24, 2016
Disease(s): Malignant Peripheral Nerve Sheath Tumour (MPNST)
Intervention(s): Pembrolizumab
Locations: Oslo university Hospital, Oslo, Norway
Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors
Status: Recruiting
Last Changed: Dec 05, 2019
First Received: May 04, 2017
Disease(s): Malignant Peripheral Nerve Sheath Tumors
Locations: Moffitt Cancer Center, Tampa, Florida, United States
Johns Hopkins, Baltimore, Maryland, United States
National Institutes of Health (NIH), Bethesda, Maryland, United States
Dana Farber Cancer Institute, Boston, Massachusetts, United States
University of Minnesota, Minneapolis, Minnesota, United States
... and 7 other locations.
PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors
Status: Recruiting
Last Changed: Mar 02, 2020
First Received: Oct 22, 2015
Disease(s): Sarcoma, Malignant Peripheral Nerve Sheath Tumors
Intervention(s): PLX3397, Sirolimus
Locations: Early Drug Development Center, Boston, Massachusetts, United States
Washington University in St. Louis, Saint Louis, Missouri, United States
Columbia University, New York, New York, United States
Vaccine Therapy in Treating Patients With Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery
Status: Recruiting
Last Changed: May 29, 2020
First Received: Mar 07, 2016
Disease(s): Metastatic Malignant Peripheral Nerve Sheath Tumor, Neurofibromatosis Type 1, Recurrent Malignant Peripheral Nerve Sheath Tumor
Intervention(s): Computed Tomography, Laboratory Biomarker Analysis, Oncolytic Measles Virus Encoding Thyroidal Sodium Iodide Symporter, Quality-of-Life Assessment, Single Photon Emission Computed Tomography
Locations: Mayo Clinic, Rochester, Minnesota, United States
SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors
Status: Recruiting
Last Changed: Jun 04, 2020
First Received: Feb 14, 2018
Disease(s): Malignant Peripheral Nerve Sheath Tumors, Neurofibromatosis 1
Intervention(s): Selumetinib, Sirolimus
Locations: Children's National Medical Center, Washington, District of Columbia, United States
Johns Hopkins University, Baltimore, Maryland, United States
National Cancer Institute, Bethesda, Maryland, United States
Washington University, Saint Louis, Missouri, United States
Testing Whether Cancers With Specific Mutations Respond Better to Glutaminase Inhibitor, CB-839 HCl, Anti-Cancer Treatment, BeGIN Study
Status: Recruiting
Last Changed: Jun 26, 2020
First Received: Mar 13, 2019
Disease(s): Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, NF1 Mutation Positive Malignant Peripheral Nerve Sheath Tumor, Unresectable Malignant Solid Neoplasm
Intervention(s): Pharmacodynamic Study, Telaglenastat Hydrochloride
Locations: Moffitt Cancer Center-International Plaza, Tampa, Florida, United States
Moffitt Cancer Center - McKinley Campus, Tampa, Florida, United States
Moffitt Cancer Center, Tampa, Florida, United States
University of Kentucky/Markey Cancer Center, Lexington, Kentucky, United States
National Cancer Institute Developmental Therapeutics Clinic, Bethesda, Maryland, United States
... and 6 other locations.
Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors
Status: Recruiting
Last Changed: Jul 02, 2020
First Received: Jan 10, 2020
Disease(s): Advanced Solid Tumors, Metastatic Pancreatic Cancer, Pediatric Solid Tumor, Advanced Breast Cancer, Malignant Peripheral Nerve Sheath Tumor
Intervention(s): Metarrestin
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Selinexor in Combination With Ixazomib for the Treatment of Advanced Sarcoma
Status: Not yet recruiting
Last Changed: Jan 23, 2020
First Received: Mar 19, 2019
Disease(s): Liposarcoma, Malignant Peripheral Nerve Sheath Tumors, Alveolar Soft Part Sarcoma, Ewing Sarcoma, Sarcoma
Intervention(s): Selinexor, Ixazomib
Locations: Columbia University Medical Center, New York, New York, United States
Natural History Study of Patients With Neurofibromatosis Type I
Status: Recruiting
Last Changed: Jun 18, 2020
First Received: Jun 18, 2009
Disease(s): Neurofibromatosis Type 1, Malignant Peripheral Nerve Sheath Tumor, Plexiform Neurofibroma, Optic Glioma, Neurofibroma
Locations: National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
Status: Recruiting
Last Changed: Jul 02, 2020
First Received: Jul 15, 2016
Disease(s): Acinar Cell Carcinoma, Adenoid Cystic Carcinoma, Adrenal Cortex Carcinoma, Adrenal Gland Pheochromocytoma, Anal Canal Neuroendocrine Carcinoma, Anal Canal Undifferentiated Carcinoma, Angiosarcoma, Apocrine Neoplasm, Appendix Mucinous Adenocarcinoma, Bartholin Gland Transitional Cell Carcinoma, Basal Cell Carcinoma, Bladder Adenocarcinoma, Cervical Adenocarcinoma, Cervical Clear Cell Adenocarcinoma, Cholangiocarcinoma, Chordoma, Colorectal Squamous Cell Carcinoma, Desmoid-Type Fibromatosis, Endometrial Transitional Cell Carcinoma, Endometrioid Adenocarcinoma, Esophageal Neuroendocrine Carcinoma, Esophageal Undifferentiated Carcinoma, Extrahepatic Bile Duct Carcinoma, Extramammary Paget Disease, Fallopian Tube Adenocarcinoma, Fallopian Tube Transitional Cell Carcinoma, Fibromyxoid Tumor, Gallbladder Carcinoma, Gastric Neuroendocrine Carcinoma, Gastric Squamous Cell Carcinoma, Gastric Undifferentiated Carcinoma, Gastrointestinal Stromal Tumor, Gestational Trophoblastic Tumor, Giant Cell Carcinoma, Intestinal Neuroendocrine Carcinoma, Intrahepatic Cholangiocarcinoma, Lung Carcinoid Tumor, Lung Sarcomatoid Carcinoma, Major Salivary Gland Carcinoma, Malignant Odontogenic Neoplasm, Malignant Peripheral Nerve Sheath Tumor, Malignant Testicular Sex Cord-Stromal Tumor, Metaplastic Breast Carcinoma, Metastatic Malignant Neoplasm of Unknown Primary, Minimally Invasive Lung Adenocarcinoma, Mixed Mesodermal (Mullerian) Tumor, Mucinous Adenocarcinoma, Mucinous Cystadenocarcinoma, Nasal Cavity Adenocarcinoma, Nasal Cavity Carcinoma, Nasopharyngeal Carcinoma, Nasopharyngeal Papillary Adenocarcinoma, Nasopharyngeal Undifferentiated Carcinoma, Oral Cavity Carcinoma, Oropharyngeal Undifferentiated Carcinoma, Ovarian Adenocarcinoma, Ovarian Clear Cell Adenocarcinoma, Ovarian Germ Cell Tumor, Ovarian Mucinous Adenocarcinoma, Ovarian Squamous Cell Carcinoma, Ovarian Transitional Cell Carcinoma, Pancreatic Acinar Cell Carcinoma, Pancreatic Neuroendocrine Carcinoma, Paraganglioma, Paranasal Sinus Adenocarcinoma, Paranasal Sinus Carcinoma, Parathyroid Gland Carcinoma, PEComa, Peritoneal Mesothelioma, Pituitary Gland Carcinoma, Placental Choriocarcinoma, Primary Peritoneal High Grade Serous Adenocarcinoma, Pseudomyxoma Peritonei, Rare Disorder, Scrotal Squamous Cell Carcinoma, Seminal Vesicle Adenocarcinoma, Seminoma, Serous Cystadenocarcinoma, Small Intestinal Adenocarcinoma, Small Intestinal Squamous Cell Carcinoma, Solid Neoplasm, Spindle Cell Neoplasm, Squamous Cell Carcinoma of the Penis, Teratoma With Somatic-Type Malignancy, Testicular Non-Seminomatous Germ Cell Tumor, Thyroid Gland Carcinoma, Tracheal Carcinoma, Transitional Cell Carcinoma, Ureter Adenocarcinoma, Ureter Squamous Cell Carcinoma, Urethral Adenocarcinoma, Urethral Squamous Cell Carcinoma, Vaginal Adenocarcinoma, Vaginal Squamous Cell Carcinoma, Not Otherwise Specified, Vulvar Carcinoma
Intervention(s): Biospecimen Collection, Ipilimumab, Nivolumab
Locations: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
University of South Alabama Mitchell Cancer Institute, Mobile, Alabama, United States
Anchorage Associates in Radiation Medicine, Anchorage, Alaska, United States
Anchorage Radiation Therapy Center, Anchorage, Alaska, United States
Alaska Breast Care and Surgery LLC, Anchorage, Alaska, United States
... and 934 other locations.