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Diamond Blackfan Anemia

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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 1-10 of 17 results.
Safety and Efficacy Study of Sotatercept in Adults With Transfusion Dependent Diamond Blackfan Anemia
Status: Recruiting
Last Changed: May 27, 2019
First Received: Nov 03, 2011
Disease(s): Diamond Blackfan Anemia
Intervention(s): Sotatercept, Sotatercept with prednisone boost
Locations: North Shore- LIJ campus of The Feinstein Institute for Medical Research, Manhasset, New York, United States
The Use of Trifluoperazine in Transfusion Dependent DBA
Status: Recruiting
Last Changed: Sep 17, 2019
First Received: May 29, 2019
Disease(s): Diamond Blackfan Anemia, Pure Red Cell Aplasia
Intervention(s): Trifluoperazine
Locations: The Feinstein Institute for Medical Research, Manhasset, New York, United States
Diamond Blackfan Anemia Registry (DBAR)
Status: Recruiting
Last Changed: Jul 23, 2019
First Received: Mar 21, 2005
Disease(s): Anemia, Blood Disease
Locations: Cohen Children's Medical Center of NY, New Hyde Park, New York, United States
T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias
Status: Recruiting
Last Changed: Nov 13, 2019
First Received: Aug 31, 2018
Disease(s): Sickle Cell Anemia, Beta-thalassemia Major, Diamond-blackfan Anemia
Intervention(s): CD3/CD19 depleted leukocytes, CD45RA depleted leukocytes, Hydroxyurea, Rituximab, Alemtuzumab, Fludarabine, Thiotepa
Locations: Children's Hosptial of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States
Cancer in Inherited Bone Marrow Failure Syndromes
Status: Recruiting
Last Changed: Dec 09, 2019
First Received: Nov 30, 2001
Disease(s): Diamond Blackfan Anemia, Dyskeratosis Congenita, Fanconi Anemia, Shwachman Diamond Syndrome, Inherited Bone Marrow Failure Syndrome, Aplastic Anemia
Locations: National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation
Status: Recruiting
Last Changed: Mar 14, 2019
First Received: Oct 21, 2013
Disease(s): Bone Marrow Failure Syndrome, Severe Aplastic Anemia, Severe Congenital Neutropenia, Amegakaryocytic Thrombocytopenia, Diamond-Blackfan Anemia, Schwachman Diamond Syndrome, Primary Immunodeficiency Syndromes, Acquired Immunodeficiency Syndromes, Histiocytic Syndrome, Familial Hemophagocytic Lymphocytosis, Lymphohistiocytosis, Macrophage Activation Syndrome, Langerhans Cell Histiocytosis (LCH), Hemoglobinopathies, Sickle Cell Disease, Sickle Cell-beta-thalassemia
Intervention(s): CD34 Stem Cell Selection Therapy
Locations: Morgan Stanley Children's Hospital, New York-Presbyterian, Columbia University, New York, New York, United States
Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation
Status: Recruiting
Last Changed: May 21, 2019
First Received: May 01, 2018
Disease(s): Bone Marrow Failure Syndrome, Thalassemia, Sickle Cell Disease, Diamond Blackfan Anemia, Acquired Neutropenia in Newborn, Acquired Anemia Hemolytic, Acquired Thrombocytopenia, Hemophagocytic Lymphohistiocytoses, Wiskott-Aldrich Syndrome, Chronic Granulomatous Disease, Common Variable Immunodeficiency, X-linked Lymphoproliferative Disease, Severe Combined Immunodeficiency, Hurler Syndrome, Mannosidosis, Adrenoleukodystrophy
Intervention(s): Thiotepa--single daily dose, Thiotepa--escalated dose
Locations: UF Health Shands Children's Hospital, Gainesville, Florida, United States
Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies
Status: Recruiting
Last Changed: Sep 25, 2019
First Received: Jul 01, 2014
Disease(s): Sickle Cell Disease, Transfusion Dependent Alpha- or Beta- Thalassemia, Diamond Blackfan Anemia, Paroxysmal Nocturnal Hemoglobinuria, Glanzmann Thrombasthenia, Severe Congenital Neutropenia, Shwachman-Diamond Syndrome, Non-Malignant Hematologic Disorders
Intervention(s): Reduced Toxicity Ablative Regimen, Reduced Intensity Preparative Regimen, Myeloablative Preparative Regimen
Locations: University of Minnesota Medical Center, Fairview, Minneapolis, Minnesota, United States
AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion
Status: Not yet recruiting
Last Changed: Sep 23, 2019
First Received: Sep 23, 2019
Disease(s): Acute Leukemia, Severe Aplastic Anemia, Non-hodgkin Lymphoma, Hodgkin Lymphoma, Kostmann, Diamond Blackfan Anemia, Amegakaryocytic Thrombocytopenia, Sickle Cell Disease, Beta-Thalassemia
Intervention(s): alpha beta depletion
Locations: New York Medical College, Valhalla, New York, United States
Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders
Status: Recruiting
Last Changed: Mar 22, 2017
First Received: Dec 31, 2012
Disease(s): Chronic Kidney Disease, Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML), Chronic Lymphocytic Leukemia (CLL), Non-Hodgkin's Lymphoma (NHL), Hodgkin Disease, Multiple Myeloma, Myelodysplastic Syndrome (MDS), Aplastic Anemia, AL Amyloidosis, Diamond Blackfan Anemia, Myelofibrosis, Myeloproliferative Disease, Sickle Cell Anemia, Autoimmune Diseases, Thalassemia
Intervention(s): Haploidentical Bone Marrow/Kidney
Locations: Massachusetts General Hospital, Boston, Massachusetts, United States